@Duke-NUS Medical School
Focusing on glaucoma research, a neurodegenerative disease of the optic nerve, we aim to find ways to restore vision in patients with this disease.
Combining basic science research with current clinical practices, we aim to establish novel and improved therapies to retore vision in patients with glaucoma.
We aim to understand the underlying mechanism of eye diseases, especially in glaucoma, and look for therapeutic strategies for vision recovery.
We focus on glaucoma disease, looking at the eye injury response and recovery process, as well as the underlying molecular and cellular mechanisms.
Using both in vivo and in vitro models, combine with different cutting-edge technologies and technique to reveal neural functional recovery process.
We have discovered that retinal ganglion cells in mice enter into a “comatose” non-functional state after injury but retain the capacity for functional recovery.
Dr. Jonathan Crowston obtained his medical degree at the Royal Free Hospital SOM, London, and a PhD at University College London. Following ophthalmology training at Moorfields Eye Hospital, he completed glaucoma fellowships at Westmead Hospital in Sydney and the University of California, San Diego. He was subsequently appointed as a faculty member in the University of California, San Diego, and served as Director of the Hamilton Glaucoma Center Basic Research Laboratories. He moved to Melbourne in July 2006 and established the Glaucoma Research Laboratory at the Centre for Eye Research Australia (CERA). He was subsequently appointed as Head of Ophthalmology at the University of Melbourne and Director of CERA. His research focuses on understanding why ageing predisposes individuals to optic nerve damage in glaucoma, and developing new therapeutic approaches to boost neuronal repair.